Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis
نویسندگان
چکیده
منابع مشابه
the investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
Major Histocompatibility Complex: Disease Associations
Human major histocompatibility complex (MHC) alleles can be used as markers for a wide variety of autoimmune and other disorders. The interpretation of and possible bases for these associations can be considered in relation to conserved extended MHC haplotypes (CEHs). The latter are fixed stretches of up to several million base pairs of genomic deoxyribonucleic acid (DNA). CEHs constitute at le...
متن کاملIdentification and characterization of major histocompatibility complex class IIB alleles from three species of European ranid frogs
Immune genes of the major histocompatibility complex (MHC) are among the most polymorphic genes in the vertebrate genome. Due to their polymorphic nature, they are often used to assess the adaptive genetic variability of natural populations. This study describes the first molecular characterization of 13 partial MHC class IIB sequences from three European ranid frogs. The utility of previously...
متن کاملAbsence of strong linkage disequilibrium between odorant receptor alleles and the major histocompatibility complex.
The odorant receptor (OR) genes constitute the largest gene family among vertebrates. While over 800 loci are present in the human genome, their allele diversity is still poorly characterized. It has been hypothesized that the products of OR genes can be relevant in the reproductive context, thereby interacting with products of genes of the major histocompatibility complex (MHC). Here we invest...
متن کاملAssociation between HLA class II alleles and autoimmune hepatitis type 1 in Thai patients.
OBJECTIVE To investigate the association between HLA class II alleles and autoimmune hepatitis (AIH) type I in Thai patients. MATERIAL AND METHOD The clinical data of 50 autoimmune hepatitis patients type I (AIH) at Siriraj hepatitis clinic were analysed, 37 of whom were tested for HLA class II genotyping using polymerase chain reaction and sequence-specific oligonucleotide technique (PCR-SSO...
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ژورنال
عنوان ژورنال: Hepatology
سال: 1997
ISSN: 0270-9139,1527-3350
DOI: 10.1002/hep.510250211